An article in the Business section of the Sunday New York Times suggests that testosterone replacement therapy has become a marketing bonanza with sales of popular drugs like Androgel to treat “low-T” becoming blockbusters. The problem of course is that a lot of the trend is driven by profits and not necessarily effective research. Simple tests for low-T are so general that anyone stressed or depressed could fail them. For instance, do you have low energy or decreased libido? Many middle aged men might say yes when the underlying cause could be stress. Instead of using drugs with potentially harmful side effects like increased incidence of heart disease or cancer, psychotherapy or behavioral change is far safer and perhaps just as effective longer term. There simply isn’t enough research to keep up with all the marketing hype. Sound familiar? Money from drug sales often outcompetes the hard work of behavioral change. As always, sometimes drugs are necessary but many times they are simply profit centers for big business.