Patients with cancer are at increased risk for both suicidal ideation and completed suicide due to a combination of biological and psychological factors that must be addressed to increase quality of life.,Unique to cancer is that the risk of suicide persists more than 15 years past diagnosis.4

In addition to increased suicide risk, patients with head and neck cancers have higher depression scores than the general population even before a cancer diagnosis, leading to the question whether this subset of patients are struggling with a biological cause in addition to diagnosis-related symptoms.5 Complicating these cases is the well-known association of many head and neck cancers with tobacco, alcohol, and other substance use, leading to the question of whether the pre-existing mood disorders lead to substance use that increases the risk of cancer.,Depression is a major risk factor, as it is in the general population, but the cancer population is at higher baseline risk for depression, which has been linked to immunological changes.12 Identification and treatment of depression in cancer patients has been shown to decrease morbidity and mortality.13 read more

The OC Health Care Agency reported 658 new cases of the coronavirus on Tuesday, Feb. 16, increasing the cumulative total in the county to 243,163  cases since tracking began.,The data on deaths in the county is compiled from death certificates or gathered through the course of case investigations and can take weeks to process.,An estimated 8,455 cases of the virus have been recorded in Orange County in the last 14 days.,The county’s breakdown of deaths by age is as follows:

85 and older: 32.96% (1,193, up 14) read more

The end-of-day totals from California public health websites for Tuesday, Feb. 16, registered 8,855 people needing hospital care, a 61.3% drop since the Jan. 1 high of 22,853.,Reports for Tuesday, indicated a 75.9% drop in the 14-day total of 10,208 new cases from a Jan. 1 high of 42,268.,And the 14-day average of 401.9 new deaths represents a 26% decline since its Feb. 1 high of 543.1.,California communities reported 11,236 new cases of the coronavirus on Tuesday, bringing the total number of cases to 3,478,579.,There were 388 new deaths reported Tuesday, for a total of 47,507 people in California who have died from the virus.

5:16 p.m.: In diverse Stockton, people of color still underrepresented in vaccination People of color in California are still underrepresented among COVID vaccine recipients, even in Stockton, which U.S. News and World Report ranked last year as the most racially diverse city in the country.,According to the Associated Press, as more people are vaccinated and the daily number of COVID-19 cases and deaths drop, public health officials are starting to relax on containment strategies.,While stressing that people should avoid close contact — including sex — with anyone outside their household, the city’s public health department told the San Francisco Chronicle it was updating guidance it first issued last year “to reflect the latest science on COVID-19.”,12:09 p.m.: Some fitness trainers got vaccine as 'health care workers'

Some fitness trainers in California were able to get vaccinated against COVID-19 after state health officials created a loophole that helped them qualify as health care workers.,KGO-TV reports that in January, the California Department of Public Health released updated guidelines on vaccination allocation that classified outdoor recreation as health care, the first tier eligible to get the vaccine along with people over 75. read more

A paper published in the journal Nature Communications, reveals a potential revolutionary drug combination that -- in animal studies and in world-first 3D models of the tumour -- is "spectacularly effective in eradicating the cancer cells," according to lead researcher and paediatric oncologist Associate Professor c from the Children's Cancer Institute and Sydney Children's Hospital.,These models have been used to show that DIPG can bypass the activity of DFMO by pumping polyamines into cancer, essentially allowing the tumour to continue growing despite treatment with DFMO.,They have now made the breakthrough discovery that treatment with a new developmental drug, AMXT 1501, potently blocks the transport of polyamines into the DIPG cancer cell.,Treatment with AMXT 1501 was found to re-sensitize the DIPG cells to DFMO leading to what Associate Professor Ziegler said, "was a spectacular response in animal models, with a significantly increased survival and minimal toxicity (side effects).",Associate Professor Ziegler said that clinical trials of the drug combination in DIPG are planned to begin this year in children in a global study led by the Children's Cancer Institute and the Kid's Cancer Centre at Sydney Children's Hospital.

A paper published today 12 Feb 2021 in the prestigious journal, Nature Communications, reveals a potential revolutionary drug combination that - in animal studies and in world-first 3D models of the tumor - is "spectacularly effective in eradicating the cancer cells," according to lead researcher and pediatric oncologist Associate Professor David Ziegler, from the Children's Cancer Institute and Sydney Children's Hospital.,These models have been used to show that DIPG can bypass the activity of DFMO by pumping polyamines into cancer, essentially allowing the tumor to continue growing despite treatment with DFMO.,They have now made the breakthrough discovery that treatment with a new developmental drug, AMXT 1501, potently blocks the transport of polyamines into the DIPG cancer cell.,Treatment with AMXT 1501 was found to re-sensitize the DIPG cells to DFMO leading to what Associate Professor Ziegler said, "was a spectacular response in animal models, with a significantly increased survival and minimal toxicity (side effects)".,Associate Professor Ziegler said that clinical trials of the drug combination in DIPG are planned to begin this year in children in a global study led by the Children's Cancer Institute and the Kid's Cancer Centre at Sydney Children's Hospital.

A paper published in the journal Nature Communications, reveals a potential revolutionary drug combination that -- in animal studies and in world-first 3D models of the tumour -- is "spectacularly effective in eradicating the cancer cells," according to lead researcher and paediatric oncologist Associate Professor c from the Children's Cancer Institute and Sydney Children's Hospital.,These models have been used to show that DIPG can bypass the activity of DFMO by pumping polyamines into cancer, essentially allowing the tumour to continue growing despite treatment with DFMO.,They have now made the breakthrough discovery that treatment with a new developmental drug, AMXT 1501, potently blocks the transport of polyamines into the DIPG cancer cell.,Treatment with AMXT 1501 was found to re-sensitize the DIPG cells to DFMO leading to what Associate Professor Ziegler said, "was a spectacular response in animal models, with a significantly increased survival and minimal toxicity (side effects).",Associate Professor Ziegler said that clinical trials of the drug combination in DIPG are planned to begin this year in children in a global study led by the Children's Cancer Institute and the Kid's Cancer Centre at Sydney Children's Hospital.

By The Associated Press

MINNEAPOLIS — Minnesota health officials urged this week that people wear masks — and wear them properly — as the state reported an additional 964 new infections on Saturday.,Louisiana has registered 9,276 confirmed coronavirus deaths, 16th highest in the U.S. read more

For the past four days, the Shelby County Health Department has reported new coronavirus cases in the 400-500 range.,There were 533 COVID-positive patients in area hospital beds as of 5 p.m. Thursday, according to the Tennessee Healthcare Resource Tracking System.,About 40% of patients in area ICU beds were COVID-positive (149) or suspected of having the coronavirus (8).,About 19% of patients in area acute care beds were either COVID-positive (384) or suspected of having the coronavirus (38).,As of Wednesday, the agency reported 670,482 total coronavirus cases, including 8,232 deaths, 2,964 current hospitalizations and 596,883 inactive cases (recoveries).

More than 250,000 Indiana residents age 70 and older have scheduled appointments to receive the first dose of a COVID-19 vaccine, including more than 125,000 people age 70 to 79 who scheduled vaccines Wednesday, the first day of that age group's eligibility, the Indiana State Department of Health said Thursday.,To combat a spike in cases, Noble County has implemented a new set of pandemic restrictions, as most of northeast Indiana remains in the red, county health officials said Thursday.,The public health order authorized by Dr. Terry Gaff, Noble County's health officer, states the Noble County Health Department will not accept or approve plans for any social gatherings or events where attendance is expected to exceed the attendance limits outlined in Holcomb's order.,Noble County's capacity limits extend to all facilities or individuals that host social gatherings and events, including but not limited to entertainment venues, sports venues, restaurants, bars, taverns, nightclubs and other establishments providing in-person food and drink service.”,Sporting events in Noble County must also adhere to the governor's order, but the Noble County Health Department may approve additional spectator attendance “upon submission of a safety plan submitted seven days in advance of the event.”