Patients with cancer are at increased risk for both suicidal ideation and completed suicide due to a combination of biological and psychological factors that must be addressed to increase quality of life.,Unique to cancer is that the risk of suicide persists more than 15 years past diagnosis.4

In addition to increased suicide risk, patients with head and neck cancers have higher depression scores than the general population even before a cancer diagnosis, leading to the question whether this subset of patients are struggling with a biological cause in addition to diagnosis-related symptoms.5 Complicating these cases is the well-known association of many head and neck cancers with tobacco, alcohol, and other substance use, leading to the question of whether the pre-existing mood disorders lead to substance use that increases the risk of cancer.,Depression is a major risk factor, as it is in the general population, but the cancer population is at higher baseline risk for depression, which has been linked to immunological changes.12 Identification and treatment of depression in cancer patients has been shown to decrease morbidity and mortality.13 read more

5:16 p.m.: In diverse Stockton, people of color still underrepresented in vaccination People of color in California are still underrepresented among COVID vaccine recipients, even in Stockton, which U.S. News and World Report ranked last year as the most racially diverse city in the country.,According to the Associated Press, as more people are vaccinated and the daily number of COVID-19 cases and deaths drop, public health officials are starting to relax on containment strategies.,While stressing that people should avoid close contact — including sex — with anyone outside their household, the city’s public health department told the San Francisco Chronicle it was updating guidance it first issued last year “to reflect the latest science on COVID-19.”,12:09 p.m.: Some fitness trainers got vaccine as 'health care workers'

Some fitness trainers in California were able to get vaccinated against COVID-19 after state health officials created a loophole that helped them qualify as health care workers.,KGO-TV reports that in January, the California Department of Public Health released updated guidelines on vaccination allocation that classified outdoor recreation as health care, the first tier eligible to get the vaccine along with people over 75. read more

A paper published in the journal Nature Communications, reveals a potential revolutionary drug combination that -- in animal studies and in world-first 3D models of the tumour -- is "spectacularly effective in eradicating the cancer cells," according to lead researcher and paediatric oncologist Associate Professor c from the Children's Cancer Institute and Sydney Children's Hospital.,These models have been used to show that DIPG can bypass the activity of DFMO by pumping polyamines into cancer, essentially allowing the tumour to continue growing despite treatment with DFMO.,They have now made the breakthrough discovery that treatment with a new developmental drug, AMXT 1501, potently blocks the transport of polyamines into the DIPG cancer cell.,Treatment with AMXT 1501 was found to re-sensitize the DIPG cells to DFMO leading to what Associate Professor Ziegler said, "was a spectacular response in animal models, with a significantly increased survival and minimal toxicity (side effects).",Associate Professor Ziegler said that clinical trials of the drug combination in DIPG are planned to begin this year in children in a global study led by the Children's Cancer Institute and the Kid's Cancer Centre at Sydney Children's Hospital.

A paper published today 12 Feb 2021 in the prestigious journal, Nature Communications, reveals a potential revolutionary drug combination that - in animal studies and in world-first 3D models of the tumor - is "spectacularly effective in eradicating the cancer cells," according to lead researcher and pediatric oncologist Associate Professor David Ziegler, from the Children's Cancer Institute and Sydney Children's Hospital.,These models have been used to show that DIPG can bypass the activity of DFMO by pumping polyamines into cancer, essentially allowing the tumor to continue growing despite treatment with DFMO.,They have now made the breakthrough discovery that treatment with a new developmental drug, AMXT 1501, potently blocks the transport of polyamines into the DIPG cancer cell.,Treatment with AMXT 1501 was found to re-sensitize the DIPG cells to DFMO leading to what Associate Professor Ziegler said, "was a spectacular response in animal models, with a significantly increased survival and minimal toxicity (side effects)".,Associate Professor Ziegler said that clinical trials of the drug combination in DIPG are planned to begin this year in children in a global study led by the Children's Cancer Institute and the Kid's Cancer Centre at Sydney Children's Hospital.

A paper published in the journal Nature Communications, reveals a potential revolutionary drug combination that -- in animal studies and in world-first 3D models of the tumour -- is "spectacularly effective in eradicating the cancer cells," according to lead researcher and paediatric oncologist Associate Professor c from the Children's Cancer Institute and Sydney Children's Hospital.,These models have been used to show that DIPG can bypass the activity of DFMO by pumping polyamines into cancer, essentially allowing the tumour to continue growing despite treatment with DFMO.,They have now made the breakthrough discovery that treatment with a new developmental drug, AMXT 1501, potently blocks the transport of polyamines into the DIPG cancer cell.,Treatment with AMXT 1501 was found to re-sensitize the DIPG cells to DFMO leading to what Associate Professor Ziegler said, "was a spectacular response in animal models, with a significantly increased survival and minimal toxicity (side effects).",Associate Professor Ziegler said that clinical trials of the drug combination in DIPG are planned to begin this year in children in a global study led by the Children's Cancer Institute and the Kid's Cancer Centre at Sydney Children's Hospital.

BATON ROUGE, La. – The LSU women's basketball team travels to face No. 1 South Carolina on Sunday, February 14 at 11 a.m. CT in Colonial Life Arena in Columbia, South Carolina.,Aifuwa continues to lead LSU with 8.8 rebounds per game and 24 blocked shots this season, and is the second-leading scorer on the team with 11.9 points per game.,Sophomore , a strong candidate for SEC Sixth Player of the Year honors, is providing a key spark off the bench averaging 9.6 points and 4.1 rebounds per game and is second in shooting at 44.2 percent from the field.,For the 2020-21 season, seating for LSU women's basketball games will be general admission in the PMAC.,To order tickets for any of LSU's last two women's basketball home games, go to LSUtix.net.

(Photo by Brian Davidson/Getty Images)

After 16 seasons of covering MLB (13 with the Kansas City Royals and three with the St. Louis Cardinals), Joel Goldberg opens up and reflects on covering the game he loves and the people he has met along his journey of telling stories as a broadcast journalist.,This book does more though than just talk baseball though, as Joel tells stories about those in the world of business along with average everyday people who play a small role that has made a difference in the lives of others.,Scattered throughout the book are touching stories about “small ball” individuals from Kansas City who have overcome challenges.,The book tells emotional stories that include a relationship between former Royals pitcher Bruce Chen and a young Royals pitching prospect named Carlos Fortuna.,Toward the end of the book, Goldberg tells another story about the late Yordano Ventura and how he was one of the most energetic and most respected teammates during the Royals’ multiple trips to the World Series. read more

To stay motivated to work out, you should set achievable, time-based goals that you can measure, like 'exercise for 20 minutes five days a week.',Examples of SMART goals include:  Run my first 5k in the next three months Exercise for 20 minutes every day  Be able to do 20 push-ups by the end of next month

Setting smaller "process" goals, which you can achieve along the way to a larger goal, can also keep you motivated, says Jen Kates, a certified personal trainer, and health coach, and founder of Shift Human Performance.,A 2009 study looked at adults' intrinsic goals for exercise, such as improving health and advancing exercise skills, and extrinsic goals, such as enhancing their image.,For example, if you can only find time for 15 minutes of exercise a day, that's okay.,Insider's takeaway  To stay motivated to work out, try setting SMART goals, switching workouts, or finding a workout buddy or group. read more

January 10, 2021

Phil Marsh has a strong appreciation for downtown Mount Airy dating to his childhood, when many fond memories were made there.,In addition to his service with the DBA, Marsh owns two older buildings on North Main Street, including one housing an office for his electrical contracting business, which has further entrenched him in downtown Mount Airy.,Being an only child meant Phil Marsh probably spent more time in the fields than youths from larger families, whether it included priming tobacco, topping the plants or other tasks.,Yet the lessons of hard work learned early in life have helped define Phil Marsh as a person who continues to put in many hours with his electrical business and community endeavors.,Spearheading events read more

January 10, 2021

Phil Marsh has a strong appreciation for downtown Mount Airy dating to his childhood, when many fond memories were made there.,In addition to his service with the DBA, Marsh owns two older buildings on North Main Street, including one housing an office for his electrical contracting business, which has further entrenched him in downtown Mount Airy.,Being an only child meant Phil Marsh probably spent more time in the fields than youths from larger families, whether it included priming tobacco, topping the plants or other tasks.,Yet the lessons of hard work learned early in life have helped define Phil Marsh as a person who continues to put in many hours with his electrical business and community endeavors.,Spearheading events read more